循证医学 Evidence-based Clinical Prac...

沈建通

目录

  • 1 基本理论与方法
    • 1.1 循证实践概述（Introduction）
      • 1.1.1 最佳证据的涵义
      • 1.1.2 证据分级的涵义
      • 1.1.3 证据分级标准
      • 1.1.4 临床经验的涵义
      • 1.1.5 患者价值观的涵义
    • 1.2 问题构建（Forming Questions ）
      • 1.2.1 问题构建技巧
      • 1.2.2 临床问题构建案例
      • 1.2.3 PICO问题构建模式
    • 1.3 证据查找（Finding the Evidence）
      • 1.3.1 各类问题的证据类型选用
      • 1.3.2 利用6S模型查找最佳证据
      • 1.3.3 证据来源选择
      • 1.3.4 PubMed数据库检索
    • 1.4 证据评价（Critical Appraisal of Evidence）
      • 1.4.1 干预性研究证据的评价与使用
      • 1.4.2 诊断试验证据的评价与使用
      • 1.4.3 危害/病因研究证据的评价与使用
      • 1.4.4 预后研究证据的评价与使用
      • 1.4.5 系统评价证据的评价与使用
    • 1.5 临床问题循证实践
      • 1.5.1 危害问题循证实践（Harm Scenario）
      • 1.5.2 诊断问题循证实践（Diagnosis Scenario）
      • 1.5.3 治疗问题循证实践 (Single Trials) Scenario
      • 1.5.4 治疗问题循证实践(Systematic Review) Scenario
      • 1.5.5 预后问题循证实践（Prognosis Scenario）
    • 1.6 证据综合：Meta分析
    • 1.7 循证实践案例（Practice Case）
      • 1.7.1 案例2
      • 1.7.2 案例3
    • 1.8 拓展学习工具与资源（EBM Library）
      • 1.8.1 教育处方
      • 1.8.2 自我评价方法
      • 1.8.3 EBM相关计算工具
      • 1.8.4 术语
  • 2 实践探索
    • 2.1 循证护理
    • 2.2 循证全科医学
    • 2.3 循证补充替代医学
    • 2.4 循证外科
    • 2.5 循证老年医学
    • 2.6 循证采购
    • 2.7 循证新生儿学
    • 2.8 循证精神卫生
    • 2.9 循证危重症
    • 2.10 发展中国家的EBM
  • 3 课程课件
    • 3.1 循证医学概述
    • 3.2 问题构建
    • 3.3 证据分类分级
    • 3.4 证据来源与检索
    • 3.5 医学研究设计概述
    • 3.6 疾病的测量与分布
    • 3.7 病因与病因推断
    • 3.8 描述性研究
    • 3.9 队列研究
    • 3.10 病例对照研究
    • 3.11 实验性研究
    • 3.12 诊断性试验
    • 3.13 诊断问题循证实践
    • 3.14 预后研究
  • 4 教学视频
    • 4.1 循证医学总论
    • 4.2 问题的构建
    • 4.3 证据的检索
    • 4.4 患者价值观与意愿
    • 4.5 病因研究证据的评价与应用
    • 4.6 诊断性证据的评价与应用
    • 4.7 防治性证据的评价与应用
    • 4.8 预后研究证据的评价与应用
    • 4.9 患者安全
拓展学习工具与资源（EBM Library）


核心阅读

随机对照试验

额外阅读

  • Bad Pharma: How Medicine is Broken, and How We Can Fix It by Ben Goldacre

  • Medical Statistics at a Glance Paperback – by Aviva Petrie, Caroline Sabin

  • Statistics Toolkit – by Rafael Perera, Carl Heneghan, and Douglas Badenoch.

  • How to Read a Paper: The Basics of Evidence-Based Medicine by Trisha Greenhalgh.

  • Clinical Epidemiology: How to Do Clinical Practice Research by R.Brian Haynes , David L. Sackett , Gordon H. Guyatt

检索工具

These are filtered versions of search engines. They allow you to search information and websites that have met specified criteria “” this avoids irrelevant sites or sites containing unreliable material.

  • National Library for Health (NLH) Specialist Libraries (including PUBMED)

  • TRIP (Turning Research Into Practice) database

  • Cochrane Library

证据评价表格

其他资源

文献评价指南

  • Users’ guides to the medical literature. II. How to use an article about therapy or prevention. A. Are the results of the study valid? JAMA 1993 Dec 1; 270(21):2598-601

  • Evidence-Based Medicine Working Group: Guyatt GH; Sackett DL; Cook DJ. Users’ guides to the medical literature. III. How to use an article about a diagnostic test. A. Are the results of the study valid?. JAMA 1994 Feb 2; 271(5):389-91. Evidence-Based Medicine Working Group: Jaeschke R ; Guyatt G ; Sackett DL

系统评价系列

  • Systematic reviews: synthesis of best evidence for clinical decisions. Ann Intern Med 1997 Mar 1; 126(5):376-80

  • Cook DJ; Mulrow CD; Haynes RB. Systematic reviews: critical links in the great chain of evidence Ann Intern Med 1997 Mar 1; 126(5):389-91.

  • Mulrow CD; Cook DJ; Davidoff F. Using numerical results from systematic reviews in clinical practice. Ann Intern Med 1997 May 1; 126(9):712-20

  • McQuay HJ; Moore RA. How consumers and policymakers can use systematic reviews for decision making. Ann Intern Med 1997 July 1; 127(1): 37-42

  • Bero LA; Jadad AR. Getting research findings into practice: Closing the gap between research and practice: an overview of systematic reviews of interventions to promote the implementation of research findings. BMJ 1998 15 Aug; 317(7156): 465-468

  • Bero LA, Grilli R, Grimshaw JM, Harvey E, Oxman AD, Thomson MA. Getting research findings into practice: Implementing research findings in developing countries. BMJ 1998 22 Aug; 317(7157): 531-535 Garner P, Kale R, Dickson R, Dans T, Salinas R

循证实践相关文献

  • Making better use of research findings. BMJ 1998 4 July; 317(7150): 72-75

  • Haines A, Donald A. Barriers and bridges to evidence based clinical practice. BMJ 1998 25 July; 317(7153): 273-276: 273-276

  • Haynes B, Haines A. How do primary care physicians seek answers to clinical questions? A literature review. Journal of the Medical Library Association 2006, 94(1), pp55-60

  • Coumou HCH, Meijman FJ. Sicily statement on evidence-based practice. BMC Medical Education 2005, 5:1

  • Dawes M, et al. Getting research findings into practice: finding information on clinical effectiveness. British Medical Journal 1998, 317(7152), pp200-203

  • Glanville J, et al. When less is more: a practical approach to searching for evidence-based answers Journal of the Medical Library Association 2002, 90(3), pp298-304

  • Grandage KK et al. The impact of evidence on physicians’ inpatient treatment decisions. Journal of General Internal Medicine 2004, 5(1), pp402-409

  • Lucas BP et al. Evidence-based medicine and the practicing clinician. Journal of General Internal Medicine 1999, 14(4), pp236-242

  • McAlister FA, et al. What do evidence-based secondary journals tell us about the publication of clinically important articles in primary healthcare journals? BMC Medicine, 2004, 2:3

  • McKibbon KA, et al. Review of the usefulness of contacting other experts when conducting a literature search for systematic reviews British Medical Journal 1998, 317(7172), pp1562-156

书籍

  • Statistics Toolkit   Buy now. by Rafael Perera, Carl Heneghan and Douglas Badenoch

  • Online resources (includes cited papers, further reading and Excel calculators)

  • Evidence-Based Medicine Toolkit (2nd Ed)   Buy now. by Carl Heneghan and Douglas Badenoch