目录

  • 1 基本理论与方法
    • 1.1 循证实践概述(Introduction)
      • 1.1.1 最佳证据的涵义
      • 1.1.2 证据分级的涵义
      • 1.1.3 证据分级标准
      • 1.1.4 临床经验的涵义
      • 1.1.5 患者价值观的涵义
    • 1.2 问题构建(Forming Questions )
      • 1.2.1 问题构建技巧
      • 1.2.2 临床问题构建案例
      • 1.2.3 PICO问题构建模式
    • 1.3 证据查找(Finding the Evidence)
      • 1.3.1 各类问题的证据类型选用
      • 1.3.2 利用6S模型查找最佳证据
      • 1.3.3 证据来源选择
      • 1.3.4 PubMed数据库检索
    • 1.4 证据评价(Critical Appraisal of Evidence)
      • 1.4.1 干预性研究证据的评价与使用
      • 1.4.2 诊断试验证据的评价与使用
      • 1.4.3 危害/病因研究证据的评价与使用
      • 1.4.4 预后研究证据的评价与使用
      • 1.4.5 系统评价证据的评价与使用
    • 1.5 临床问题循证实践
      • 1.5.1 危害问题循证实践(Harm Scenario)
      • 1.5.2 诊断问题循证实践(Diagnosis Scenario)
      • 1.5.3 治疗问题循证实践 (Single Trials) Scenario
      • 1.5.4 治疗问题循证实践(Systematic Review) Scenario
      • 1.5.5 预后问题循证实践(Prognosis Scenario)
    • 1.6 证据综合:Meta分析
    • 1.7 循证实践案例(Practice Case)
      • 1.7.1 案例2
      • 1.7.2 案例3
    • 1.8 拓展学习工具与资源(EBM Library)
      • 1.8.1 教育处方
      • 1.8.2 自我评价方法
      • 1.8.3 EBM相关计算工具
      • 1.8.4 术语
  • 2 实践探索
    • 2.1 循证护理
    • 2.2 循证全科医学
    • 2.3 循证补充替代医学
    • 2.4 循证外科
    • 2.5 循证老年医学
    • 2.6 循证采购
    • 2.7 循证新生儿学
    • 2.8 循证精神卫生
    • 2.9 循证危重症
    • 2.10 发展中国家的EBM
  • 3 课程课件
    • 3.1 循证医学概述
    • 3.2 问题构建
    • 3.3 证据分类分级
    • 3.4 证据来源与检索
    • 3.5 医学研究设计概述
    • 3.6 疾病的测量与分布
    • 3.7 病因与病因推断
    • 3.8 描述性研究
    • 3.9 队列研究
    • 3.10 病例对照研究
    • 3.11 实验性研究
    • 3.12 诊断性试验
    • 3.13 诊断问题循证实践
    • 3.14 预后研究
  • 4 教学视频
    • 4.1 循证医学总论
    • 4.2 问题的构建
    • 4.3 证据的检索
    • 4.4 患者价值观与意愿
    • 4.5 病因研究证据的评价与应用
    • 4.6 诊断性证据的评价与应用
    • 4.7 防治性证据的评价与应用
    • 4.8 预后研究证据的评价与应用
    • 4.9 患者安全
证据评价(Critical Appraisal of Evidence)

After we have searched for the evidence, we need to decide if it is both valid and important before deciding if we can apply the evidence to our individual patients. The order in which we consider validity and importance depends on individual preference.

证据评价的步骤

首先你需要证据评价工具(评价工具可在本页下载),利用这些工具指导你完成证据的评价。

NoteThis tool was created for your own personal use and testing purposes. Medical decisions should NOT be based solely on the results of this program. Although this program has been tested thoroughly, we are not responsible for any damages or loss of information. Please use at your own risk.

证据评价工具下载:

  • 系统评价证据评价表




  • 诊断证据评价表


  • 危害证据评价表


  • 预后证据评价表


  • 系统评价(用于治疗问题)评价表


  • 治疗证据评价表


定性研究证据评价


1. 研究结果真是吗?Are the Results Valid (i.e., Are the Study Methods Strong/Rigorous?)


To figure out if the research results are valid, you need to examine the research methodology! Examining the research methodology means basically questioning every choice the researcher made in conducting the study (that they published).

You are looking for internal consistency between the quantitative or qualitative research design and the researcher’s choices. For example, for RCTs you’d want to find answers to: what specific type of trial design was used? how were the subjects chosen? what was the sample size? were the subjects randomized? were the subjects similar at the start of the study? was the attrition rate acceptable? was an intention-to-treat analysis performed? were the research instruments valid and reliable? etc. 

This question is at the heart of critical appraisal because if the study methods are not valid, then you CANNOT BELIEVE THE RESULTS

If the methods are suspect, you CANNOT BELIEVE the results and, therefore, should not waste your time reading the rest of the paper. Go find another study!

2.研究结果有意义吗?Are the Research Results/Findings Important?


If you’ve decided that the research methods are valid, then you can continue to read the study. At this point you want to look at the actual results or findings. So that means looking at the quantitative (numbers/stats) or qualitative findings (e.g., themes or theory).

For quantitative results, what is the relative risk, absolute risk, risk reduction, odds ratio, likelihood ratio, hazard ratio — whatever is appropriate for the type of study conducted. You want to evaluate the magnitude of the result (how big) and the significance of the result (statistical and clinical significance). 

For qualitative findings, you want to reflect on the themes that the researcher identified from the participant data. Do the themes make sense with what the researcher reported about the participants? Do the themes make sense with the data? In other words, are the qualitative findings reliable and valid?

If the study was necessary, the methods strong, and the results statistically and clinically significant, then you can make a decision about how to translate the findings into your professional or advanced nursing practice. 

3. 研究结果适用于我的患者吗?Can I Apply the Results to My Patient or Patient’s Situation?


This is the ultimate question, isn’t it? How do we translate research and evidence into practice so that it will benefit our patient? 

You shouldn’t just use the research results or study findings on any patient. You first want to decide if your patient is similar to the sample used in the study. Look at the age range of the sample population, disease state, comorbidities, health status, etc. If your patient is NOT similar to the study sample, you can’t be confident that the treatment will perform in the manner described in the study article. 

If your patient is a good match for the study sample, then you have to decide if the treatment will be acceptable or feasible in your particular practice setting. Not all settings will have the resources, or inclination, to treat the patients with evidence from the newest study. 

Before talking with the healthcare team and the patient, the last consideration is whether the benefits of the new treatment will outweigh the potential risks or harms to the patient. 

主要临床问题证据评价案例

Which type of evidence would you like to appraise?