研究领域

主要从事药用天然产物活性成分的分离与分析，药物代谢动力学，药物信息学等方向研究。在液质联用（LC-MS/MS），生物分析方面有丰富的科研经验。

论文与著作

1. *Qiuhua Zhang, *Lingyi Huang, Youjia Wu, Liying Huang, Xiaowen Xu and Renyi Lin. Study on Quality Control of Compound Anoectochilus roxburghii (Wall.) Lindl. by Liquid Chromatography – Tandem Mass Spectrometry. Molecules 2022, 27, 4130. (*co-corresponding author)

   
   

2. *Lingyi Huang, *Yu Zhou, Yizhi Wang, Min Lin. Optimization of S-Nitrosocaptopril Monohydrate Storage Conditions Based on Response Surface Method. Molecules 2021, 26(24), 7533. (*co-first author)

   
   

3. Xiaoling Yu, Lingyi Huang, Chen You, Liying Huang. Hepatoprotective effects of polysaccharide from Anoectochilus roxburghii (wall.) Lindl. on rat liver injury induced by CCl4. Drug Des Dev Ther. 2021 Jul 6; 15:2885-2897.

   
   

4. *Xiaowen Xu, *Lingyi Huang, Youjia Wu, Lijuan Yang, Liying Huang. Synergic cloud-point extraction using [C4mim][PF6] and Triton X-114 as extractant combined with HPLC for the determination of rutin and narcissoside in Anoectochilus roxburghii (Wall.) Lindl. and its compound oral liquid. J Chromatogr B Analyt Technol Biomed Life Sci. 2021 Apr 1;1168:122589. (*co-first author)

   
   

5. Lingyi Huang, Dejan Nikolic, Richard B van Breemen. Hepatic metabolism of licochalcone A, a potential chemopreventive chalcone from licorice (Glycyrrhiza inflata), determined using liquid chromatography-tandem mass spectrometry. Anal Bioanal Chem. 2017 Dec; 409(30):6937-6948.

   
   

6. *Ke Huang, *Lingyi Huang, Richard B van Breemen. Detection of reactive metabolites using isotope-labeled glutathione trapping and simultaneous neutral loss and precursor ion scanning with ultra-high-pressure liquid chromatography triple quadruple mass spectrometry. Anal Chem. 2015 Apr 7;87(7):3646-54.  (*co-first author)

   
   

7. Lingyi Huang, Zhengui Huang, Zhiqiang Bai, Rui Xie, Liping Sun, Kejiang Lin. Development and strategies of VEGFR-2/KDR inhibitors. Future Med Chem. 2012 Sep;4(14):1839-52.