研究领域

消化系统药理学

论文与著作

1. Liu Z ^#, Tu M^#, Shi J^#,Zhou H, Meng G, Gu J*, Wang Y*.Inhibition of fucosylation by 2-fluorofucose attenuated acetaminophen-induced liver injury via its anti-inflammation and anti-oxidative stress effects.Frontiers in Pharmco.2022, 939317.

2. Tu M^#, Fan X^#, Shi J, Jing S, Xu X,Wang Y*. 2-Fluorofucose attenuates hydrogen peroxide-induced oxidative stress in HepG2 cells via Nrf2/keap1 and NF-κB signaling pathways. Life-Basel. 2022, 12,406.

3. Li X, Song S, Xu M, Hua Y, Ding Y, Shan X, Meng G,Wang Y*.Sirtuin3 deficiency exacerbates carbon tetrachloride-induced hepatic injury in mice.J Biochem Mol Toxicol. 2019, 33.

4. Wang Y^#,*, Wei J^#, Tu M, Gu J, Zhang W^*.Fucoidan Alleviates Acetaminophen-Induced Hepatotoxicity via Oxidative Stress Inhibition and Nrf2 Translocation.Int. J Mol. Sci., 2018, 19.

荣誉与奖励

近5年侧重于岩藻糖基化修饰及一些植物提取物在急性肝损伤中的作用研究，课题组主要应用分子生物学、组织与细胞形态学、药理学、基因干预等多学科方法研究各种类型肝损伤过程中岩藻糖基化修饰和一些植物提取物的作用及可能机制，着力探讨预防和治疗急性肝损伤的潜在药物和特异性生物学靶标。