黄超
  • 单位：南通大学   药理系
  • 职称：教授
  • 职位：副院长
  • 出生：1981.11
  • 性别：男
  • 社会职务： 南通大学临床药物研究所所长，江苏省药理学会理事。中国老年学和老年医学学会抗衰老分会委员；江苏省药理学会青年工作委员会副主任委员；江苏省药理学会抗炎免疫专委会副主任委员；江苏省免疫学会免疫与代谢专业委员会委员；江苏省免疫学会神经免疫专业委员会委员；中国药理学会神经精神药理专业委员会委员
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研究领域

神经精神药理学，神经免疫药理学



论文与著作

 

  1. Gu Y#, Ye T#,     Tan P#, Tong L#, Ji J, Gu Y, Shen     Z, Shen X, Lu X*, Huang C*. Tolerance-inducing effect and properties of innate immune     stimulation on chronic stress-induced behavioral abnormalities in mice. Brain     Behav Immun. 2021, 91:451–471.

  2. Lu X#, Liu H#, Cai     Z#, Hu Z#, Ye M, Gu Y, Wang Y, Wang D, Lu Q, Shen Z,     Shen X, Huang C*. ERK1/2-dependent BDNF synthesis and signaling is     required for the antidepressant effect of microglia stimulation. Brain Behav Immun. 2022, 106:147–160.

  3. Wang Y#, Hu Z#, Liu H#, Gu Y#, Ye M#, Lu Q, Lu X*, Huang C*. Adolescent microglia stimulation produces     long-lasting protection against chronic stress-induced behavioral     abnormalities in adult male mice. Brain     Behav Immun. 2022, 105:44–66.

  4. Xu X#, Hu P#,     Ma Y#, Tong L, Wang D, Wu Y, Chen Z, Huang C*. Identification of a pro-elongation effect of diallyl     disulfide, a major organosulfur compound in garlic oil, on microglial     process. J Nutr Biochem. 2020, 78:108323.

  5. Wu Y#, Gao M#, Wu J#, Hu P, Xu     X, Zhang Y, Wang D, Chen Z, Huang C*. Sulforaphane triggers a     functional elongation     of microglial process via the Akt signal. J     Nutr Biochem.     2019, 67:51–62.

  6. Huang C#, Wang P#,     Xu X#,     Zhang Y, Gong Y, Hu W, Gao M, Wu Y, Ling Y, Zhao X, Qin Y, Yang R*, Zhang     W*. The ketone body metabolite β-hydroxybutyrate induces an     antidepression-associated ramification of microglia via HDACs     inhibition-triggered Akt-small RhoGTPase activation. Glia. 2018, 66(2):256–278.

  7. Yang R#, Wang H#, Wen J, Ma K, Chen D, Chen Z, Huang C*. Regulation of microglial process elongation, a featured     characteristic     of microglial plasticity. Pharmacol Res. 2019, 139:286–297.

  8. Wang P #, Zhang YR#, Gong Yu#, Yang RR, Chen Z, Hu WF, Wu Y,     Gao MH, Xu X, Qin YB, Huang C*. Sodium butyrate triggers a functional elongation of     microglial process via Akt-small RhoGTPase activation and HDACs     inhibition. Neurobiol Dis. 2018, 111:12–25.

  9. Hu W#, Wu J#, Ye T#, Chen Z,     Tao J, Tong L, Ma K, Wen J, Wang H, Huang C*. Farnesoid X     receptor-mediated cytoplasmic translocation of CRTC2 disrupts CREB-BDNF     signaling in hippocampal CA1 and leads to the development of depression-like behaviors in     mice. Int J Neuropsychopharmacol. 2020, 26:pyaa039.

  10. Ye T#, Wang D#, Cai Z#, Tong L, Chen Z, Lu J, Lu     X, Huang C*,     Yuan X*. Antidepressive properties of macrophage-colony stimulating factor in     a mouse model of depression induced by chronic unpredictable     stress. Neuropharmacology. 2020, 172:108132.

  11. Hu P#, Wang D#, Zhang Y#, Cai Z, Ye T, Tong L, Xu X,     Lu J, Liu F, Lu X, Huang C*. Apoptosis-triggered decline in hippocampal microglia     mediates adolescent intermittent alcohol exposure-induced depression-like     behaviors in mice. Neuropharmacology. 2020,     170:108054.

  12. Cai Z#, Ye T#, Xu X#, Gao M, Zhang Y, Wang D, Gu     Y, Zhu H, Tong L, Lu J, Chen Z, Huang C*. Antidepressive properties of microglial stimulation in a     mouse model of depression induced by chronic unpredictable stress. Prog Neuropsychopharmacol Biol Psychiatry. 2020, 101:109931.

  13. Gao M#, Hu P#, Cai Z#, Wu Y,     Wang D, Hu W, Xu X, Zhang Y, Lu X, Chen D, Chen Z, Ma K, Wen J, Wang H, Huang C*.     Identification of a microglial activation-dependent antidepressant effect     of amphotericin B liposome. Neuropharmacology. 2019, 151:33–44.

  15. Wang D#, Xu X#, Wu Y,     Lin Y, Gao M, Hu P, Chen D, Lu X, Chen Z, Wang H, Huang C*. SMIP004: A     compound with     antidepressant-like activities in mouse models. Eur J Pharmacol. 2019, 843:260–267.

  16. Gong Y#, Tong L#, Yang R, Hu W, Xu X, Wang W, Wang P,     Lu X, Gao M, Wu Y, Xu X, Zhang Y, Chen Z, Huang     C*. Dynamic changes in hippocampal microglia contribute to     depressive-like behavior induced by early social isolation.Neuropharmacology. 2018, 135:223–233.

  17. Liu FG#, Wu JJ#, Gong Y, Wang P, Lei Z, Tong LJ, Chen     XF, Ling Y, Huang C*. Harmine produces antidepressant-like effects via     restoration of astrocytic functions.Prog     Neuropsychopharmacol Biol Psychiatry. 2017, 79:258–267.

  19. Wu J, Hu W, Gong Y, Wang P, Tong L, Chen X, Chen Z, Xu X, Yao W, Zhang W, Huang     C. Current pharmacological     developments in 2,3,4',5-tetrahydroxystilbene 2-O-β-D-glucoside (TSG). Eur J Pharmacol. 2017, 811:21–29.

  20. Tong JL#, Gong Y#, Wang P, Hu WF, Wang JL, Chen Z, Zhang W, Huang C*. Microglia Loss Contributes to the Development of Major     Depression Induced by Different Types of Chronic Stresses. Neurochem Res. 2017, 42:2698–2711.

  21. YangRR, Wang P, Chen Z, Hu WF, Gong Y, Zhang W, Huang C*. WY-14643, a selective agonist     of peroxisome proliferator-activated receptor-α, ameliorates     lipopolysaccharide-induced depressive-like     behaviors by preventing neuroinflammation and oxido-nitrosative stress in     mice. Pharmacol Biochem Behav. 2017, 153:97–104.

  22. Liu FG#, Hu WF#, Wang JL, Wang P, Gong Y, Tong LJ,     Jiang B, Zhang W, Qin YB, Chen Z, Yang RR, Huang C*. Z-guggulsterone Produces Antidepressant-like Effects     in Mice Through Activation of the BDNF Signaling Pathway. Int J Neuropsychopharmacol. 2017, 20:485–497.



荣誉与奖励

1、江苏省药理科学技术进步奖，靶向小胶质细胞的抑郁症发病机制及治疗策略研究，二等奖

2、江苏省高等学校科学技术研究成果奖，靶向小胶质细胞的抑郁症发病机制及防治策略研究，三等奖

3、南通大学优秀教育工作者

4、南通大学优秀党员