王淑军
  • 单位：江苏海洋大学   海洋食品与生物工程学院
  • 职称：教授
  • 职位：院长
  • 性别：女
  • 社会职务： 中国生物化学与分子生物学学会海洋分会理事、中国微生物学会微生物教学工作委员会委员、中国生物化学与分子生物学会生物化学与分子生物技术专业委员会委员、中国水产学会水产品加工和综合利用分会委员、中国生物材料学会海洋生物材料分会第二届委员会委员、江苏省食品科学与技术学会常务理事和水产食品专业委员会负责人，江苏省微生物学会副秘书长和常务理事，江苏省药学会海洋药物专业委员会副主任委员、江苏省轻工协会理事、江苏省冷链学会预制菜专业委员会副主任委员，江苏省农产品加工标准化技术委员会委员。
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研究领域

主要开展食品工程、食品加工与安全、生物技术与工程、海洋生物资源开发与利用方向的研究。



论文与著作

  1. Mingwang Liu, Yue Hao, Siyuan Wang, Siying Li, Junlan Zhou, Ming’ao Wang, Lei Zhang, Xinxing Kang**, Mingsheng Lyu, Shujun Wang,* Heterologous overproduction of a dextranase in Bacillus subtilis WB600 and its application in preparation of porous buckwheat starch, Food Bioscience, 2024,58,103636.

  2. Qiang Li, Yuehui He, Boyan Wang, Nanhai Weng, Lei Zhang, Kaichun Wang*, Fengrong Tian, Mingsheng Lyu, Shujun Wang*, Heterotrophic Nitriffcation–Aerobic Denitriffcation by Bacillus sp. L2: Mechanism of Denitriffcation and Strain Immobilization, Water, 2024, 16, 416.

  3. Boyan Wang, Yizhuo Wu, Qiang Li, Xudong Wu, Xinxin Kang*, Lei Zhang, Mingsheng Lyu, Shujun Wang*, The Screening and Identiffcation of a Dextranase-Secreting Marine Actinmycete Saccharomonospora sp. K1 and Study of Its Enzymatic Characteristics, Marine Drugs, 2024, 22, 69.

  4. Siyuan Wang, Xiuli Bao, Mingwang Liu, Qingfang Hao , Shuai Zhang, Siying Li, Lei Zhang, Xinxin Kang, Mingsheng Lyu, Shujun Wang*, Aptamer-Based Sensor for Rapid and Sensitive Detection of Offoxacin in Meat Products, Sensors, 2024，24, 1740.

  5. Xiuli Bao, Siyuan Wang, Qingfang Hao, Yue Bai, Siying Li, Shuai Zhang, Lei Zhang,  Xinxin Kang, Mingsheng Lyu, Shujun Wang*, Enroffoxacin Rapid Detection in Aquatic Foods: Based on DNA Aptamer Sensor, foods, 2024, 13, 941.

  6. Yue Hao, Mingwang Liu, Hao Ni, Yue Bai, Qingfang Hao, Lei Zhang, Xinxin Kang, Mingsheng Lyu, Shujun Wang*, Preparation of Sweet Potato Porous Starch by Marine Dextranase and Its Adsorption Characteristics, foods, 2024, 13, 549.

  7. 白玥, 郝青芳, 周俊栏, 包秀丽, 郝悦, 亢新鑫, 王淑军*, 产蛋白酶海洋细菌Bacillus sp.4sp5分离鉴定及降解南极磷虾原肌球蛋白的研究, 食品安全质量检测学报, 2024,15(04):98-105.

  8. 姚娜, 张磊, 田凤蓉, 王开春, 卢静, 王淑军*, 耐盐反硝化细菌的筛选鉴定及生长促进剂对其反硝化性能的影响研究, 化学与生物工程, 2024, 41(02):48-60.

  9. 于轶群, 薛陆州, 倪豪, 蒋蕾, 亢新鑫, 盘赛昆, 王淑军*, 海洋α-葡萄糖苷酶的克隆表达及其制备高纯潘糖的研究,食品工业科技，2024

  10. Qianru Lin, Mingwang Liu, Hao Ni, Yue Hao, Yiqun Yu, Yiran Chen, Qing Wu, Yi Shen, Lei Zhang*, Mingsheng Lyu, Shujun Wang*, High-Degree Polymerizate IMOs of Dextranase 2 Hydrolysates Enhance Lactobacillus Acid Metabolism: 3 Based on Growth, and Metabolomic and Transcriptomic 4 Analyses, LWT Food Science and Technology, 2023, 187, 115345.

  11. Jingfei Hu, Xiaohua Lai, Xudong Wu, Huanyu Wang, Nanhai Weng, Jing Lu, Mingsheng Lyu, Shujun Wang*, Isolation of a Novel Anti-Diabetic α-Glucosidase Oligo-Peptide Inhibitor from Fermented Rice Bran, Foods, 2023, 12, 183.

  12. Huanyu Wang, Qianru Lin, Mingwang Liu, Wen Ding, Nanhai Weng, Hao Ni, Jing Lu*, Mingsheng Lyu，Shujun Wang*，Molecular Docking and Site-Directed Mutagenesis of GH49 Family Dextranase for the Preparation of High-Degree Polymerization Isomaltooligosaccharide, Biomolecules，2023, 13.

  13. Baojie Dou, Xudong Wu, Zihan Xia, Guanghao Wu, Quanyou Guo, Mingsheng Lyu*, Shujun Wang*, Multiple Bioactivities of Peptides from Hydrolyzed Misgurnus anguillicaudatus, Molecules, 2023, 28, 2589.

  14. Hind Boualis, Xudong Wu, Boyan Wang, Qiang Li, Mingwang Liu, Lei Zhang*, Mingsheng Lyu, Shujun Wang*, Dextranase Production Using Marine Microbacterium sp. XD05 and Its Application, Marine Drugs, 2023, 21, 528.

  15. Xudong Wu, Baojie Dou, Boyan Wang, Mingwang Liu, Ruxue Shao, Jing Lu*, Mingsheng Lyu, Shujun Wang*. Improved Stability and Hydrolysates of Hyperthermophilic GH57 Type II Pullulanase from the Deep-Sea Archaeon Thermococcus siculi HJ21 by Truncation，Catalysts, 2023, 13, 453.

  16. Qingzhen Miao, Wen Ding, Xiuli Bao, Siyuan Wang, Qianru Lin, Yingying Xu, Jing Lu, Mingsheng Lyu, Shujun Wang*, An efficient DNAzyme for the fluorescence detection of Vibrio cholera, Food Science and Nutrition, 2023.

  17. Yingying Xu, Huanyu Wang, Qianru Lin, Qingzhen Miao, Mingwang Liu, Hao Ni, Lei Zhang*, Mingsheng Lyu, Shujun Wang*, Immobilization of dextranase obtained from the marine Cellulosimicrobium sp. Y1 on nanoparticles: nano-TiO2 improving hydrolysate properties and enhancing reuse, Nanomaterials, 2023.

  18. Na Yao, Lei Zhang*, Fengrong Tian, Kaichun Wang, Qiang Li, Jing Lu, Mingsheng Lyu, Shujun Wang*, Compound Sodium Nitrophenolate Promotes Denitrification by Nitrifying Bacteria by Upregulating Nitrate Reductase, Applied Sciences, 2023, 13, 6134.

  19. Qingfang Hao, Yue Bai, Haolong Zhou, Xiuli Bao, Huanyu Wang, Lei Zhang*, Mingsheng Lyu, Shujun Wang*, Isolation and Characterization of Bacteriophage VA5 against Vibrio alginolyticus, Microorganisms, 2023,11.

  20. 包瑞璇，周皓隆，方再郗，卢静，吕明生，王淑军*，大菱鲆肠道乳杆菌Lactobacillus sp.N5的筛选鉴定及其抑制水产病原菌的研究, 水产学杂志，2023，36(03)：38-45.

  21. 钱佳琪，翁南海，卢静，吕明生，王淑军*，食品污水中异养硝化-好氧反硝化菌Bacillus sp.JG441的筛选鉴定及其脱氮特性，化学工程师，2023,37(06)：45-52.

  22. 翁南海，王焕宇，张磊，田凤蓉，王开春，王淑军*，一株耐盐反硝化细菌的筛选、鉴定和特性及其产物四氢嘧啶的检测，微生物学通报，2023，50(06)：2335−2348.

  23. 翁南海，张磊，卢静，田凤蓉，王开春，王淑军*，一株耐盐反硝化细菌的筛选鉴定及其在高盐废水脱氮中的应用.江苏海洋大学学报(自然科学版),2023,32(03):31-37.

  24. 郝青芳，高永龙，桂云霞，付晓萍，王淑军*，双酶法制备紫薯三七花复合饮料，食品研究与开发，2023，44(06)：72-77.

  25. 孟欣，张磊，丁闻，田凤蓉，王开春，王淑军*.耐盐菌Halomonas alimentaria NY处理高盐废水的研究.化工管理,2023(23):61-64.

  26. Jie Hu, Cang Wang, Hangtian Zu, Zaixi Fang, Haolong Zhou, Junlan Zhou, ShujunWang*, Mingsheng Lyu*, Nano-SiO2 inhibits the marine aquatic pathogen Vibrio parahaemolyticus, Aquaculture Reports, 2022,23,101015.

  27. Xueqing Tian, Jinfei Hu, Tong Wei, Wen Ding, Qingzhen Miao, Zhe Ning, Shihui Fan, Hangjie Wu, Jing Lu, Mingsheng Lyu*, Shujun Wang*, Fast and sensitive graphene oxide-DNAzyme-based biosensor for Vibrio alginolyticus detection, Journal of Fish Diseases, 2022.

  28. 魏桐，包瑞璇，丁闻，吴广浩，卢静，吕明生，王淑军*，一种来自海洋细菌Virgibacillus sp.sp2T的豌豆蛋白加工蛋白酶，食品科技，2022，47(06)：8-15.

  29. 王藏，马小艺，田小鹏，祖航天，丁延帅，吕明生，王淑军*，海洋细菌Pseudoalteromonas sp.HL9的筛选鉴定及产磷脂酶B性质，食品科学，2022，43(02)：134-141.

  30. Xiaoyi Ma, Wen Ding, Cang Wang, Hangjie Wu, Xiaopeng Tian, Mingsheng Lyu*, Shujun Wang*, DNAzyme biosensors for the detection of pathogenic bacteria, Sensors and Actuators: B. Chemical, 2021, 331:129422.

  31. Xiaoyi Ma, Cang wang, Mingcan Qin, Xiaopeng Tian, Shihui Fan, Hangtian Zu, Mingsheng Lyu*, Shujun Wang*, Rapid detection of Aeromonas hydrophila with a DNAzyme-based sensor, Food Control, 2021,123:107829.

  32. Jingfei Hu, Xueqing Tian, Tong Wei, Hangjie Wu, Jing Lu, Mingsheng Lyu, Shujun Wang*, Anti-Helicobacter pylori Activity of a Lactobacillus sp. PW-7 Exopolysaccharide, Foods，2021, 10. 2453.

  33. Shihui Fan, Chao Ma, Xiaopeng Tian, Xiaoyi Ma, Mingcan Qin, Hangjie Wu, Xueqing Tian, Jing Lu, Mingsheng Lyu*, Shujun Wang*, Detection of Vibrio vulnificus in Seafood With a DNAzyme-Based Biosensor, Front. Microbiol. 2021,

  34. Mingcan Qin，Xiaoyi Ma，Shihui Fan，Hangjie Wu，Wanli Yan，Xiaopeng Tian，Jing Lu，Mingsheng Lyu*，Shujun Wang*, Rapid detection of Pseudomonas aeruginosa using a DNAzyme-based sensor, Food Science & Nutrition, 2021,

  35. Hangjie Wu, Lide Gu, Xiaoyi Ma, Xueqing Tian, Shihui Fan, Mingcan Qin, Jing Lu, Mingsheng Lyu*, Shujun Wang*, Rapid Detection of Helicobacter pylori by the Naked Eye Using DNA Aptamers, ACS Omega, 2021, 6, 5, 3771-3779.

  36. Cang Wang, Xiaoyi Ma, Jie Hu, Xiaopeng Tian, Hao Zhang, Dongxue Dong, Zaixi Fang, Mingsheng Lyu, Shujun Wang*, Jing Lu*. Nanolayered Double Hydroxide Inhibits the Pathogenicity of Vibrio parahaemolyticus, Journal of Nanomaterials, 2021.

  37. Yanshuai Ding, Hao Zhang, Xuelian Wang, Hangtian Zu, Cang Wang, Dongxue Dong, Mingsheng Lyu, Shujun Wang*, Immobilization of Dextranase on Nano-Hydroxyapatite as a Recyclable Catalyst, Materials, 2021,14,130

  38. Dongxue Dong, Xuelian Wang, Tian Deng, Zhe Ning, Xiaopeng Tian,Hangtian Zu, Yanshuai Ding, Cang Wang, Shujun Wang, Mingsheng Lyu*, A novel dextranase gene from the marine bacterium Bacillus aquimaris S5 and its expression and characteristics, FEMS Microbiology Letters, 2021, 368(3)

  39. Zhe Ning, Dongxue Dong, Xiaopeng Tian, Hangtian Zu, Xueqing Tian, Mingsheng Lyu, Shujun Wang*, Alkalic dextranase produced by marine bacterium Cellulosimicrobium sp. PX02 and its application，Journal of Basic Microbiology,2021.

  40. 张皓，祖航天，胡杰，吕明生，王淑军*.一种产碱性葡聚糖蔗糖酶菌株的筛选、鉴定及其合成低聚糖的研究[J].食品科技，2021,46(07):22-28.

  41. 秦铭灿，田雪晴，周俊栏，方再郗，周皓隆，高仁姣，吕明生，王淑军*.基于核酸适配体的生物传感技术检测食源性致病菌研究进展[J].食品安全质量检测学报，2021，12(13):5237-5243.

  42. 董冬雪，王焕宇，王雪莲，张皓，魏桐，胡经飞，吕明生，王淑军*.海洋右旋糖酐酶分子改造及其催化性质研究[J].江苏海洋大学学报(自然科学版)，2021,30(02):16-21.

  43. 王芳芳，田小鹏，刘雪芹，祖航天，王 藏，胡杰，吕明生，王淑军*，产右旋糖酐酶菌株的筛选、鉴定及酶学性质研究[J].中国酿造,2021,40(04):77-83.

  44. Tian Deng, Yanli Feng, Linxiang Xu, Xiaopeng Tiana, Xiaohua Lai, Mingsheng Lyu*, Shujun Wang*, Expression, purification and characterization of a cold-adapted dextranase from marine bacteria and its ability to remove dental plaque, Protein Expression and Purification, 2020, 174:105678.

  45. Xueqin Liu, Yanli Feng, Xiaohua Lai, Tian Deng, Xin Liu, Mingsheng Lyu*, Shujun Wang*, Virgibacillus halodenitrificans ST-1 for Fermentation of Shrimp Paste and Hydrolysates of its Protease，Food Science & Nutrition，2020, 1777

  46. Xin Liu, Tian Deng, Xueqin Liu, Xiaohua Lai, Yanli Feng, Mingsheng Lyu*, Shujun Wang*, Isomalto-Oligosaccharides Produced by Endodextranase Shewanella sp. GZ-7 From Sugarcane Plants, Natural Product Communications, 2020, 15(9):1-10

  47. Yanli Feng, Tian Deng, Xiaohua Lai, Zhihua Feng, Mingsheng Lyu*, Shujun Wang*, Effect of Properties of Silver Nanoparticles Coated by Polar Material and the Antibacterial Activity for Marine Pathogenic Bacteria, Journal of Nanomaterials, 2020,11

  48. Wei Ren, Po-Jung Jimmy Huang, Meilin He, Mingsheng Lu, Changhai Wang*, Shujun Wang*, Juewen Liu*. Sensitivity of a classic DNAzyme for Pb2+ modulated by cations, anions and buffers, Analyst, 2020, 145(4): 1384-1388.

  49. 赖晓桦, 邓 甜, 胡经飞, 陈德宁, 吕明生, 王淑军*, 米糠发酵产物抑制α 葡萄糖苷酶的工艺优化, 食品工业科技，2020, 42(4):128-134.

  50. Wei Ren, Yanshuai Ding, Lide Gu, Wanli Yan, Cang Wang, Mingsheng Lyu, Changhai Wang*, Shujun Wang*, Characterization and mechanism of the effects of Mg–Fe layered double hydroxide nanoparticles on a marine bacterium: new insights from genomic and transcriptional analyses, Biotechnology for Biofuels, 2019,12:196

  51. Wei Ren, Le Liu, Lide Gu, Wanli Yan, Yan li Feng, Dongxue Dong, Shujun Wang*, Mingsheng Lyu, Changhai Wang*, Crystal Structure of GH49 Dextranase from Arthrobacter oxidans KQ11: Identification of Catalytic Base and Improvement of Thermostability Using Semirational Design Based on B‑Factors, Journal of Agricultural and Food Chemistry, 2019, 67, 4355−4366.

  52. Wei Ren, Po-Jung Jimmy Huang, Meilin He, Mingsheng Lu, Shujun Wang*, Changhai Wang*, Juewen Liu*. The Two Classic Pb2+‐selective DNAzymes Are Related: Rational Evolution for Understanding Metal Selectivity, ChemBioChem, 2019, 20:1-6.

  53. Lide Gu, Wanli Yan, Hangjie Wu, Shihui Fan, Wei Ren, Shujun Wang*, Mingsheng Lyu*, Juewen Liu*, Selection of DNAzymes for Sensing Aquatic Bacteria: Vibrio Anguillarum, Analytical Chemistry, 2019, 91(12):7887−7893.

  54. Wanli Yan, Lide Gu, Wei Ren, Xiaoyi Ma, Mingcan Qin, Mingsheng Lyu*, Shujun Wang*, Recognition of Helicobacter pylori by protein-targeting aptamers, 2019, Helicobacter，2019, 24(3):1-10.

  55. Hongfei Liu, Wei Ren, Mingsheng Ly, Haifeng Li*, Shujun Wang*, Characterization of an Alkaline GH49 Dextranase from Marine Bacterium Arthrobacter oxydans KQ11 and Its Application in the Preparation of Isomalto-Oligosaccharide, Marine Drugs, 2019,17:479.

  56. Xiaohua Lai, Xin Liu, Xueqin Liu, Tian Deng, Yanli Feng, Xiaopeng Tian, Mingsheng Lyu*, Shujun Wang*, The Marine Catenovulum agarivorans MNH15 and Dextranase: Removing Dental Plaque, Marine Drugs, 2019,17:592.

  57. Le Liu, Yi Ding, Shu Liu, Shujun Wang, Yaowei Fang, Mingsheng Lyu*, Dextrans removal from sugarcane juice using dextranase from marine bacterium Arthrobacter oxydans KQ11, Quality Assurance and Safety of Crops & Foods, 2019, 11(1):53-59.

  58. Wei Ren, Ruanhong Cai, Wanli Yan, Mingsheng Lyu, Yaowei Fang, Shujun Wang*, Purification and characterization of a biofilm-degradable dextranase from a marine bacterium, Marine Drugs, 2018, 16(2), 51-67.

  59. Yi Ding, Le Liu, Yaowei Fang, Xu Zhang, Mingsheng Lyu*, Shujun Wang*, The Adsorption of Dextranase onto Mg/Fe-Layered Double Hydroxide: Insight into the Immobilization, Nanomaterials, 2018, 8(3): 173-186.

  60. Wanli Yan, Lide Gu, Shu Liu, Wei Ren, Mingsheng Lyu*, Shujun Wang*, Identification of a highly specific DNA aptamer for Vibrio vulnificus using systematic evolution of ligands by exponential enrichment coupled with asymmetric PCR, Journal of Fish Diseases, 2018:41(12):1821-1829.

  61. Lide Gu, Wanli Yan, Shu Liu, Wei Ren, Mingsheng Lyu*, Shujun Wang*, Trypsin enhances aptamer screening: A novel method for targeting proteins, Analytical Biochemistry, 2018,561:89-95.

  62. Lide Gu, Runjhun Saran, Wanli Yan, Po-Jung Jimmy Huang, Shujun Wang*, Mingsheng Lyu*, Juewen Liu*, Reselection Yielding a Smaller and More Active Silver-Specific DNAzyme, ACS Omega, 2018, 3, 15174−15181.

  63. Huaixu Cheng, Zhidan Luo, Mingsheng Lyu, Song Gao*, Shujun Wang*, The hyperthermophilic alpha-amylase from Thermococcus sp. HJ21 does not require exogenous calcium for thermostability because of high-binding affinity to calcium, Journal of Microbiology, 2017, 55(5):379–387.

  64. Wei Ren, Shujun Wang*, Mingsheng Lyu, Xiaobei Wang, Yaowei Fang, Yuliang Jiao, Jianen Hu*, Optimization of four types of antimicrobial agents to increase the inhibitory ability of marine Arthrobacter oxydans KQ11 dextranase mouthwash, Chinese Journal of Oceanology and Limnology, 2016, 34(2):354-366.

  65. Xiaobei Wang, Huaixu Cheng, Mingsheng Lyu, Yaowei Fang, Yuliang Jiao, Weijuan Li, Gengmao Zhao, Shujun Wang*, Dextranase from Arthrobacter oxydans KQ11-1 inhibits biofilm formation by polysaccharide hydrolysis, Biofouling（3区）, 2016, 32(10): 1223–1233.

  66. Delong Wang, Mingsheng Lu, Shujun Wang*, Yuliang Jiao, Weijuan Li, Qiang Zhu, Zhaopu Liu*, Purification and characterization of a novel marine Arthrobacter Oxydans KQ11 dextranase, Carbohydrate Polymers, 2014, 106:71-76.

  67. Delong Wang, Mingsheng Lu, Xiaobei Wang, Yuliang Jiao, Yaowei Fang, Zhaopu Liu*, Shujun Wang*, Improving stability of a novel dextran-degrading enzyme from marine Arthrobacter oxydans KQ11, Carbohydrate Polymers, 2014,103, 294-299.

  68. Yuliang Jiao, Shujun Wang*, Mingsheng Lu, Binghua Jiao, Weijuan Li, Yaowei Fang, Shuliu，Characterization of a marine-derived dextranase and its application to the prevention of dental caries. Journal of Industrial Microbiology Biotechnology, 2014, 41(1) :17-26.

  69. Ruanhong Cai, Mingsheng Lu, Yaowei Fang, Yuliang Jiao, Qiang Zhu, Zhaopu Liu*, Shujun Wang*, Screening, production, and characterization of dextranase from Catenovulum sp. Annals of Microbiology, 2014, 64:147-155.

  70. Xiaobei Wang, Mingsheng Lu, Shujun Wang*, Yaowei Fang, Delong Wang, Wei Ren, Gengmao Zhao*, The atmospheric and room temperature plasma method (ARTP) on the dextranase activity and structure, International Journal of Biological Macromolecules, 2014,70:284-291.


荣誉与奖励


全国“五一劳动奖章”获得者、“江苏省333高层次人才培养工程”中青年科学技术带头人、江苏省“六大人才高峰”培养对象、连云港市“521工程”第一层次培养对象。“生物工程”江苏省“十四五”重点学科带头人，“海洋科学”江苏省优势学科“海洋生物资源开发利用”方向带头人。


1. 江苏省科学技术奖三等奖：海洋微生物新型工业酶产业化应用关键技术（2019，1/7）

2. 国家海洋科学技术奖二等奖：医学组织工程材料海洋生物胶原蛋白评价技术（2017，4/10）

3. 中国轻工业联合会科学技术发明奖三等奖：海洋微生物新型工业酶产业化应用关键技术（2019，1/6）

4. 江苏省轻工业科学技术奖励技术发明奖一等奖：新型海洋酶制剂开发关键技术与应用（2019，1/5）

5. 江苏省轻工业科学技术奖励三等奖：新型海洋热稳定不依赖钙离子的超高温耐酸淀粉酶研究（2015，1/5）