研究领域

细菌疫苗研发；药物的基础与早期临床研发；定量药理学研究

论文与著作

1.作为负责人主持2项国家自然科学基金。

2.作为第一发明人获得国家授权发明专利一项。

3.已在相关领域发表学术论文50余篇，其中SCI收录论文10余篇，CSCD收录论文20余篇。

4.作为PI或SUB-I承担40余项创新药物Ⅰ期临床试验，包括作为组长单位PI承担了我国首个重组亚单位新冠疫苗的Ⅰ期临床试验；作为PI承担EMA注册项目等。

作为副主编组织编写专著一部。

1.Yu-Ying Fu#, Liang Zhang, Yi Yang, Cheng-Wei Liu, Ying-Na He, Pan Li, Xian Yu*. synergistic antibacterial effect of ultrasound microbubbles combined with chitosan-modifed polymyxin B-loaded liposomes on bioflmproducing Acinetobacter baumannii. International Journal of Nanomedicine, 2019, 14:1805–1815 (IF5.115)  

2.Defeng Liu#, Yi Yang, Fu Kuang, Shuyun Qing, Bangqin Hu, Xian Yu*. Risk of infection with different immunosuppressive drugs combined with glucocorticoids for the treatment of idiopathic membranous nephropathy: A pairwise and network meta-analysis. International Immunopharmacology, 2019,70:354–361 (IF 3.943)  

3.Bang-Qin Hu#, Yi Yang, Chun-Jing Zhao, De-Feng Liu, Fu Kuang, Li-Jun Zhang, Xian Yu*. Accuracy of neutrophil CD64 expression in diagnosing infection in patients with autoimmune diseases: a meta-analysis. Clinical Rheumatology, 2019, 38（5）:1319-1328 （IF 2.394）

4.Yi Yang#, Xian Yu#，Fan Zhang, Yifan Xia*.  Evaluation of the effect of IVIG dosing on mortality in patients with sepsis: A network meta-analysis. Clinical Therapeutics. 2019, 41(9):1823-1838.e4 (IF 3.119) 

5.Xian Yu*, Yan Wang, Yifan Xia, Lijuan Zhang, Qin Yang, Jun Lei. A DNA vaccine encoding VP22 of herpes simplex virus type I (HSV-1) and OprF confers enhanced protection from Pseudomonas aeruginosa in mice. Vaccine, 2016, 34 (37):4399-4405. (IF:3.413)

荣誉与奖励