研究领域

中药活性物质的作用机制研究

论文与著作

1.       Zhou Jiangtao, Hou Jing, Wang J, Wang J, Gao J, Bai Y. BrusatolInhibits Laryngeal Cancer Cell Proliferation and Metastasis Via AbrogatingJAK2/STAT3 Signaling Mediated Epithelial-Mesenchymal Transition[J]. LifeSciences, 2021.

2.       Zhou Jiangtao, Wu Hao, Hou J, Wang J, Wang J, Li M, Yao X, Gao J, Zhang Q. Daurisolinealleviated experimental colitis in vivo and in vitro: Involvement of NF-κB andWnt/β-Catenin pathway. Int Immunopharmacol. 2022.

3.       Zhou Jiangtao, Ren Kaida, Hou J, Chen J, Yang G. α‑rhamnrtin‑3‑α‑rhamnoside exerts anti‑inflammatoryeffects on lipopolysaccharide‑stimulatedRAW264.7 cells by abrogating NF‑κB andactivating the Nrf2 signaling pathway. MOLECULAR MEDICINE REPORTS,2021.

4.    Zhou Jiangtao, Wang Jun, WANG Jiajing, LI Deyun, HOU Jing, LI Jiankuan, BAI Yun’e, GAOJianping. An inulin-type fructan CP-A from Codonopsis pilosula attenuates experimentalcolitis in mice through promoting autophagy-mediated inactivation of NLRP3inflammasome. Chinese Journal of Natural Medicines. 2024.

5.    Jiangtao Zhou, Deyun Li, Jiajing Wang, Zhuoyang Cheng, Changjian Wang, Xuepeng Zhang, XiexinXu and Jianping. An Inulin-Type Fructan CP-A from Codonopsis pilosulaAlleviated 5-Fluorouracil-Induced Intestinal Mucositis via the ERK/MLCK/MLC2Pathway and Regulation of Gut Microbiota. Pharmaceuticals. 2024

6.       Bai Yune, Hou Jing, Zhang XT, Gao JP, Zhou Jiangtao*. Zanthoxylumbungeanum Seed Oil Elicits Autophagy and Apoptosis in Human Laryngeal TumorCells via PI3K/AKT/mTOR Signaling Pathway[J]. Anti-cancer agents in medicinalchemistry. 2021. （通讯作者）

7.       Hou Jing, Wang Jun, Meng J, Zhang X, Niu Y, Gao J, Bai Y, ZhouJiangtao*. Zanthoxylum bungeanum seed oil attenuates LPS-induced BEAS-2Bcells activation and inflammation by inhibiting the TLR4/MyD88/NF-κB signaling.Evidence-BasedComplementary and Alternative Medicine, 2021. （通讯作者）

8.       Zhou Jiangtao, Tan Lihua, Xie Jianhui, Lai Z, Huang Y, Qu C, LuoD, Lin Z, Huang P, Su Z, Xie Y.Characterization of brusatol self-microemulsifying drug delivery system and itstherapeutic effect against dextran sodium sulfate-induced ulcerative colitis inmice[J], Drug Delivery, 2017, 24(1).

9.       Zhou Jiangtao, Li Cailan, Tan Lihua, Xu YF, Liu YH, Mo ZZ, Dou YX, Su R, Su ZR, Huang P, Xie JH. Inhibitionof Helicobacter pylori and Its Associated Urease by Palmatine: Investigation onthe Potential Mechanism[J]. PloS one,2017, 12(1): e0168944.

10.    Zhou Jiangtao, Wang Tongtong, Dou Y, Huang Y, Qu C, Gao J, Huang Z, Xie Y,Huang P, Lin Z, Su Z. Brusatol ameliorates 2, 4, 6-trinitrobenzenesulfonicacid-induced experimental colitis in Rats: Involvement of NF-κB pathway andNLRP3 inflammasome, International Immunopharmacology,2018, 64, 264-274.

11.    Zhou Jiangtao, Li Chenyang, Wang Chunhua, Wang YF, Wang XD, WangHT, Zhu Y, Jiang MM, Gao XM. Phenolic Compounds from the Roots ofRhodiola crenulata and Their Antioxidant and Inducing IFN-γ ProductionActivities[J]. Molecules, 2015,20(8):13725-39.

荣誉与奖励

1、国家自然科学基金  基于自噬-NLRP3炎性小体途径研究党参菊粉型果聚糖CPS-a治疗溃疡性结肠炎的作用机制，项目负责人。

2、山西省应用基础研究计划党参菊粉型果聚糖CPS-a调控自噬/NLRP3炎性小体作用途径抗溃疡性结肠炎的机制研究，项目负责人。

3、山西省教育厅应用创新项目基于自噬-NLRP3炎性小体途径研究党参菊粉型果聚糖CPS-a治疗溃疡性结肠炎的作用机制，项目负责人。