研究领域

肿瘤及神级系统疾病的放射性核素分子探针研发

论文与著作

[1]   JianhuaJia, Longfei Zhang, Jia Song, Jiapei Dai, MengchaoCui*. Discovery of diphenoxy derivatives with flexible linkersas ligands for β‑amyloid plaques.  Mol. Pharm., 2020, 17,4089-4100.

[2]   Liang Wang, Mengda Niu, Yujia He, ChuanhuiziTian, Zhiping Peng*, JianhuaJia*.Synthesis and evaluation of Al¹⁸F-NODAcomplex conjugated 2-(4-aminophenyl)benzothiazole as a potential tumor imagingagent. Bioorg.Med. Chem. Lett., 2020, 30(11), 127160.

[3]     Yujia He, Tingting Fu, Yuying Li, Weiwei Xue*, Mengchao Cui, Liang Wang, MengdaNiu, Zhiping Peng*, Jianhua Jia*. Flexiblemultidentate benzyldiamine derivatives with high affinity for β-amyloid in cerebral amyloidangiopathy.Mol. Divers. 2020, 10.1007/s11030-020-10098-y.

[4]    Jianhua Jia, Jia Song, Jiapei Dai, Boli Liu, Mengchao Cui*.Optically pure diphenoxy derivatives as more flexible probes for β-amyloidplaques. ACS Chemical Neuroscience, 2016, 7, 1275-1282.

[5]    Jianhua Jia, Kaixiang Zhou, Jiapei Dai, Boli Liu, MengchaoCui*. 2-Arylbenzothiazoles labeled with [CpRe/^99mTc(CO)3] andevaluated as β-amyloid imaging probes. European Journal of Medicinal Chemistry,2016, 124, 763-772.

[6]    Jianhua Jia, Mengchao Cui*, Jiapei Dai, Boli Liu. ^99mTc(CO)3-labeledbenzothiazole derivatives preferentially bind cerebrovascular amyloid:potential use as imaging agents for cerebral amyloid angiopathy. MolecularPharmaceutics, 2015, 12, 2937–2946.

[7]    Jianhua Jia, Mengchao Cui*, Jiapei Dai, Boli Liu.2-Phenylbenzothiazole conjugated with cyclopentadienyl tricarbonyl [CpM(CO)3](M = Re, Tc-99m) complexes as potential imaging probes for beta-amyloidplaques. Dalton Transactions, 2015, 44, 6406-6415.

[8]    Jianhua Jia, Mengchao Cui*, Jiapei Dai, Xuedan Wang, Yu-ShinDing, Hongmei Jia and Boli Liu. ^99mTc-labeled benzothiazole andstilbene derivatives as imaging agents for Aβ plaques in cerebral amyloidangiopathy. Medicinal Chemistry Communications, 2014, 5, 153 - 158.

获2020基础医学院课程思政创新设计大赛三等奖