研究领域

雄性生殖细胞自我更新与分化

论文与著作

1.Niu Z, Mu H, Zhu H, Wu J, Hua J.p38 MAPKpathway is essential for self-renewal of mouse male germline stem cells(mGSCs).Cell Prolif. 2017 Feb;50(1). doi: 10.1111/cpr.12314.

2.Niu Z, Siyu Wu, Chongyang Wu, Na Li,Haijing Zhu, Weishuai Liu, Jinlian Hua* Multipotent male germline stem cells(mGSCs) from neonate porcine testis Brazilian Archives of Biology andTechnology.2016, January-December Vol.59: e16150449 

3.Niu Z, Zheng L, Wu S, Mu H, Ma F, Song W,Zhu H, Wu J, He X, Hua J. Ras/ERK1/2 pathway regulates the self-renewal ofdairy goat spermatogonia stem cells. Reproduction. 2015 May;149(5):445-52. doi:10.1530/REP-14-0506. 

4.Wu J, Liao M, Zhu H, Kang K, Mu H, Song W, NiuZ, He X, Bai C, Li G, Li X, Hua J. CD49f-positive testicular cells in Saanendairy goat were identified as spermatogonia-like cells by miRNA profilinganalysis. J Cell Biochem. 2014 Oct; 115(10):1712-23. doi: 10.1002/jcb.24835. 

5.Zhu H, Ma J, Du R, Zheng L, Wu J, Song W, NiuZ, He X, Du E, Zhao S, Hua J. Characterization of immortalized dairy goat malegermline stem cells (mGSCs). J Cell Biochem. 2014 Sep;115(9):1549-60. doi:10.1002/jcb.24812.

6.Niu Z, Hu Y, Liao M, Yu M, Zhu H, Wang L,Wu J, Bai C, Li G, Hua J. Conservation and function of Dazl in promoting themeiosis of goat male germline stem cells. Mol Biol Rep. 2014 May;41(5):2697-707. doi: 10.1007/s11033-014-3156-z.Epub 2014 Jan 30. 

7.Tang F, Yao X, Zhu H, Mu H, Niu Z, Yu M,Yang C, Peng S, Li G, Hua J. Expression pattern of Ngn3 in dairy goat testisand its function in promoting meiosis by upregulating Stra8.Cell Prolif. 2014Feb; 47(1):38-47. doi: 10.1111/cpr.12077. Epub 2013 Nov 29.

8.Yu M, Mu H, Niu Z, Chu Z, Zhu H, Hua J. miR-34cenhances mouse spermatogonial stem cells differentiation by targetingNanos2.  J Cell Biochem. 2014Feb;115(2):232-42. doi: 10.1002/jcb.24655.

9.Wu J, Song W, Zhu H, Niu Z, Mu H, Lei A,Yang C, Peng S, Li X, Li G, Hua J. Enrichmentand characterization of Thy1-positive male germline stem cells (mGSCs) fromdairy goat (Capra hircus) testis using magnetic microbeads. Theriogenology.2013 Dec;80(9):1052-60. doi: 10.1016/j.theriogenology.2013.08.003. Epub 2013 Sep19. 

10.Qiu P,Song W, Niu Z, Bai Y, Li W, Pan S, Peng S, Hua J. Platelet-derived growth factor promotes the proliferation of humanumbilical cord-derived mesenchymal stem cells. Cell Biochem Funct. 2013Mar;31(2):159-65. doi: 10.1002/cbf.2870. Epub 2012 Sep 7.

11.Li M,Liu C, Zhu H, Sun J, Yu M, Niu Z, Liu W, Peng S, Hua J. Expression pattern ofBoule in dairy goat testis and its function in promoting the meiosis in malegermline stem cells (mGSCs). J Cell Biochem. 2013 Feb;114(2):294-302. doi:10.1002/jcb.24368.

12.Niu Z, HuY, Chu Z, Yu M, Bai Y, Wang L, Hua J. Germ-like cell differentiation frominduced pluripotent stem cells (iPSCs). Cell Biochem Funct. 2013Jan;31(1):12-9. doi: 10.1002/cbf.2924. Epub 2012 Oct 22.