研究领域

职业性肺疾患精准防治

论文与著作

1.Qiang Zhou, Guan Yi, Meiyu Chang, Ning Li, Yichun Bai, Haibin Li, Sanqiao Yao*. Activation of Sirtuin3 by honokiol ameliorates alveolar epithelial cell senescence in experimental silicosis via the cGAS-STING pathway. Redox Biology,2024,74:103224.

2. Haibin Li, Penghao Wang, Meng Hu, Shushuo Xu, Xinxiao Li, Deliang Xu, Kaihao Feng, Qiang Zhou, Meiyu Chang, Sanqiao Yao*. Echistatin/BYL-719 impedes epithelial-mesenchymal transition in pulmonary ffbrosis induced by silica through modulation of the Integrin β1/ILK/PI3K signaling pathway. Int Immunopharmacol, 2024,136:112368 

3. Lin Zhang, Yongheng Wang, Linqiang Tian, Long Li, Zhen Chen, Chunjie Ding, Jiaqi Tian, Dandan Song, Sanqiao Yao*, Wenjie Ren*. Thrombospondin-1-mediated crosstalk between autophagy and oxidative stress orchestrates repair of blast lung injury.BBA - Molecular Basis of Disease, 2024.167026. 

4. Ning Li, Meiyu Chang, Qiang Zhou, Lin Zhang, Yongheng Wang, Yi Guan, Haibin Li, Yingzheng Zhao, Chunjie Ding, Shan Hong, Sanqiao Yao*. Activation of AMPK signalling by Metformin: Implication an important molecular mechanism for protecting against mice silicosis via inhibited endothelial 

cell-to-mesenchymal transition by regulating oxidative stress and apoptosis. Int Immunopharmacol,2023,120.

 5. Nan Liu, Yi Guan, Yan Yu, Gai Li, Ling Xue, Weikang Li, Xiaoyu Qu, Ning Li and Sanqiao Yao*. Pulmonary effects of exposure to indium and its compounds: cross-sectional survey of exposed workers  and experimental findings in rodents. Particle and Fibre Toxicology, 2022,19(1): 69-94 

6. Ning Li, Zhang Lin, Qiang Zhou, Meiyu Chang, Yongheng Wang, Yi Guan, Haibin Li, Yingzheng Zhao, Nan Liu, Yulan Jin, Sanqiao Yao*. Metformin alleviates crystalline silica-induced pulmonary fibrosis by remodeling endothelial cells to mesenchymal transition via autophagy signaling. Ecotoxicol Environ Saf, 2022, 245 114100 

7.Yi Guan, Nan Liu, Yan Yu, Qiang Zhou, Meiyu Chang, Yongheng Wang, Sanqiao Yao. Pathological comparison of rat pulmonary models induced by silica nanoparticles and indium-tin oxide nanoparticles. Inter J Nanomed, 2022,17:4277-4292. 

8. Nan Liu, Gai Li, Yi Guan, Rui Wang, Zhanfei Ma, Linlin Zhao, Sanqiao Yao*. N-acetylcysteine alleviates pulmonary alveolar proteinosis induced by indium-tin oxide nanoparticles in male rats: involvement of the NF-κB signaling pathway. Ecotoxicol Environ Saf, 2022,241:113812 

荣誉与奖励

1. 职业安全与健康防护科普丛书. 河南省优秀科普作品特等奖. 2023.10

2. MARCO 介导 AM 凋亡调控矽肺纤维化作用及靶向干预效果评价. 河南省科技进步二等 奖.2022.10.

3. 多聚鸟苷酸干预矽肺纤维化作用机制及效果评价.中国职业安全健康学会协会科学技术一等奖. 第一完成人. 2020.12

4. 煤矿瓦斯爆炸伤分子机制与临床救治关键技术研究. 中国职业安全健康学会协会科学技术一等奖. 第八完成人. 2019.12