Educationand Qualifications

2021-recent, Research assistant, School of bioengineering, Jiangnan University;

2015-2021, Ph.D.,School of Biotechnology, Jiangnan University;

2011.8-2015.6, Bachelor of PharmaceuticalEngineering,Southwest University;

Research Field

1 Enzymeengineering based on computational design as well as directed evolution

2 Cellevolution and dynamic regulation based on synthetic biology

Recent Publication

1.       Mengfei Long, Meijuan Xu,Zhenfeng Ma, Xuewei Pan, Jiajia You, Mengkai Hu, Yu Shao, Taowei Yang, XianZhang, Zhiming Rao. Significantly enhancing production of trans-4-hydroxy-L-proline by integrated system engineering in Escherichia coli. Science advances, 6 (21), eaba2383 (2020).

2.       Mengfei Long, Meijuan Xu,Zhina Qiao, Zhenfeng Ma, Tolbert Osire, Taowei Yang, Xian Zhang, Minglong Shao,Zhiming Rao. Directed evolution of ornithine cyclodeaminase using anEvolvR-Based growth-coupling strategy for efficient biosynthesis of L-proline. ACSSynthetic Biology, 9 (7), 1855-1863 (2020).

3.       Tolbert Osire, TaoweiYang, Meijuan Xu, Xian Zhang, MengfeiLong, Noelle Kewang a Ngon, Zhiming Rao. Integrated gene engineeringsynergistically improved substrate-product transport, cofactor generation andgene translation for cadaverine biosynthesis in E. coli. International Journal of BiologicalMacromolecules, 169, 8-17 (2020).

4.       Song Liu, Xian Zhang,Fei Liu, Meijuan Xu, Taowei Yang, MengfeiLong, Junping Zhou, Tolbert Osire, Shangtian Yang, Zhiming Rao. Designingof a cofactor self-sufficient whole-cell biocatalyst system for production of1, 2-amino alcohols from epoxides. ACS synthetic biology, 8 (4), 734-743 (2019).

5.       Taowei Yang,Shuanying Liu, Huiling Liu, Mengfei Long,Pengcheng Chen, Xian Zhang, Meijuan Xu, Zhiming Rao. Semi-quantitative activityassays for high-throughput screening of higher activity gamma glutamyltransferase and enzyme immobilization to efficiently synthesize L-theanine. Journalof Biotechnology, 330, 9-16 (2020).