研究领域

1、环境中典型/新环境污染物对生物体内分析系统、繁殖功能、神经系统、微生物群落及营养代谢等方面的毒性效应及作用机理研究。

2、基于经典中医理论，筛选有效中药单体，研究其对代谢、生殖等疾病的干预效果及调控机制。

论文与著作

1、Lihua Yang, Biran Zhu*, Shanqi Zhou, et al. Mitochondrial dysfunction was involved in decabromodiphenyl ethane-induced glucolipid metabolism disorders and neurotoxicity in zebrafish larvae. Environmental Science & Technology, 2023, 57(30): 11043-11055. (SCI影响因子11.375，排名Q1)

2、Biran Zhu, Lei Lei, Yumiao Sun, et al. Niclosamide exposure at environmentally relevant concentrations efficaciously inhibited the growth and disturbed the liver-gut axis of adult male zebrafish. Environmental Science & Technology, 2022, 56: 11516-11526. (SCI影响因子11.375，排名Q1)

3、Biran Zhu, Lei Lei, Kaiyu Fu, et al. Neurotoxicity of tetrabromobisphenol A and SiO2 nanoparticle co-exposure in zebrafish and barrier function of the embryonic chorion. Science of the Total Environment, 2022, 845: 157364. (SCI影响因子10.753，排名Q1)

4、Biran Zhu, Ziniu Wang, Lei Lei, et al. Transcriptome reveals overview of Ca2+ dose-dependent metabolism disorders in zebrafish larvae after Cd2+ exposure. Journal of Environmental Sciences, 2023, 125: 480-491. (SCI影响因子6.795，排名Q1)

5、Biran Zhu*, Jian Han, Lei Lei, et al. Effects of SiO2 nanoparticles on the uptake of tetrabromobisphenol A and its impact on the thyroid endocrine system in zebrafish larvae. Ecotoxicology and Environmental Safety, 2021, 209: 111845. (SCI影响因子7.129，排名Q1)

6、Biran Zhu*, Wei He, Fan Yang, et al. High-throughput transcriptome sequencing reveals the developmental toxicity mechanisms of niclosamide in zebrafish embryo. Chemosphere, 2020, 244: 125468. (SCI影响因子8.943，排名Q1)

7、Biran Zhu*, Wei He, Shengchao Hu, et al. The fate and oxidative stress of different sized SiO2 nanoparticles in zebrafish (Danio rerio) larvae. Chemosphere, 2019, 225: 705-712. (SCI影响因子8.943，排名Q1)

8、Biran Zhu, Gang Zhao, Lihua Yang, et al. Tetrabromobisphenol A caused neurodevelopmental toxicity via disrupting thyroid hormones in zebrafish larvae. Chemosphere, 2018, 197: 353–361. (SCI影响因子8.943，排名Q1)

9、Biran Zhu, Qiangwei Wang, Yongyong Guo, et al. Effect of co-exposure to lead and decabromodiphenyl ether (BDE-209) on neurodevelopment in zebrafish larvae. Chemosphere, 2016, 144: 1646–1654. (SCI影响因子8.943，排名Q1)

10、Biran Zhu, Qiangwei Wang, Xiangfeng Wang, et al. Impact of co-exposure with lead and decabromodiphenyl ether (BDE-209) on thyroid function in zebrafish larvae. Aquatic Toxicology, 2014, 157: 186–195. (SCI影响因子5.202，排名Q1)

11、朱璧然*，李博，冯秋珍，等. 氯硝柳胺对斑马鱼幼鱼的神经毒性究. 中国寄生虫学与寄生虫病杂志, 2019, 37(5): 1–5. (北大核心；CSCD)

12、朱璧然*，李博. 氯硝柳胺对斑马鱼幼鱼甲状腺内分泌系统的影响. 中国血吸虫病防治杂志，2020, 32(1): 78–82. (北大核心；CSCD)

13、朱立一，何伟，朱璧然*. 纳米二氧化硅和铅复合暴露对斑马鱼幼鱼甲状腺内分泌系统的毒性影响. 长江流域资源与环境, 2018, 11(27): 2588–2596. (北大核心；CSCD)

14、何伟，朱立一，朱璧然*. 灭螺药氯硝柳胺急性暴露对斑马鱼胚胎/幼鱼代谢能力影响. 长江流域资源与环境, 2020, 29(12): 2679–2685. (北大核心；CSCD)

荣誉与奖励

1、2018年，湖北省青年科技晨光计划

2、2018年，基础医学院“优秀教师”

3、2020年，基础医学院青年教师教学竞赛“二等奖”

4、2023年，湖北中医药大学教学创新大赛“一等奖”