抗阿尔茨海默症药物研发与植物源生物活性肽

论文与著作

1.Sang Zhipei*,#, Wang Keren#, Bai Ping#,Wu Anguo, Shi Jian, Wenmin Liu, Zhu Gaofeng, Wang Yiling, Lan Yu, Chen Zude,Zhao Yiyang, Zhanpin Qiao, Wang Changning*, Tan Zhenghuai*. Design, synthesisand biological evaluation of novel O-carbamoyl ferulamide derivatives asmulti-target-directed ligands for the treatment of Alzheimer's disease.European Journal of Medicinal Chemistry, 2020, 194: 112265. (药物化学领域top期刊)

2.Sang Zhipei*,#, Wang Keren#, Shi Jian,Wenmin Liu, Cheng xinfeng, Zhu Gaofeng, Wang Yiling, Zhao Yiyang, Zhanpin Qiao,Wu Anguo*, Tan Zhenghuai*. The development of advanced structural framework asmulti-target-directed ligands for the treatment of Alzheimer’s disease.European Journal of Medicinal Chemistry, 2020, 192: 112180. (药物化学领域top期刊)

3.Sang Zhipei*,#, Wang Keren#, Shi Jian,Cheng xinfeng, Zhu Gaofeng, Wei Rongrui, Ma Qinge, Yu Lintao, Zhao Yiyang, TanZhenghuai*, Liu Wenmin*. Apigenin-rivastigmine hybrids as multi-target-directedligands for the treatment of Alzheimer’s disease. European Journal of MedicinalChemistry, 2020, 187: 111958. (药物化学领域top期刊)

4.Sang Zhipei*,#, Wang Keren#, ZhangPengfei, Shi Jian, Liu Wenmin*, Tan Zhenghuai*. Design, synthesis, in-silicoand biological evaluation of novel chalcone derivatives as multi-function agentsfor the treatment of Alzheimer’s disease. European Journal of MedicinalChemistry, 2019, 180: 238-252. (药物化学领域top期刊)

5.Sang Zhipei*,#, Wang Keren#, Shi Jian,Liu Wenmin*, Tan Zhenghuai*. Design, synthesis, in-silico and biologicalevaluation of novel chalcone-O-carbamate derivatives as multifunctional agentsfor the treatment of Alzheimer’s disease. European Journal of MedicinalChemistry, 2019, 178: 726-739. (药物化学领域top期刊)

6.Bai Ping#, Wang Keren#, Zhang Pengfei#,Shi Jian, Cheng Xinfeng, Zhang Qi, Zheng Cheng, Yang Jian, Lu Xiaoxia*, SangZhipei*. Development of chalcone-O-alkylamine derivatives as multifunctionalagents against Alzheimer’s disease. European Journal of Medicinal Chemistry,2019, 183: 111737. (药物化学领域top期刊)

7.Sang Zhipei*, Pan Wanli, Wang Keren, MaQinge, Yu Lintao, Yang Yan, Bai Ping, Leng Chaoliang, Xu Qian, Li Xiaoqing, TanZhenghuai, Liu Wenmin*. Design, synthesis and evaluation of novel ferulicacid-O-alkylamine derivativesas potential multifunctional agents for thetreatment of Alzheimer’s disease. European Journal of Medicinal Chemistry, 2017, 130:379-392. (药物化学领域top期刊)

8.Sang Zhipei #, Qiang Xiaoming #, Li Yan,Xu Rui, Xu Zhongcheng, Song Qing, Wang Ting, Zhang Xiaoyu, Liu Hongyan, TanZhenghuai*, Deng Yong*. Design, synthesis and evaluation ofscutellarein-O-acetamidoalkylbenzylamines as potential multifunctional agentsfor the treatment of Alzheimer's disease. European Journal of MedicinalChemistry, 2017, 135: 307-323. (药物化学领域top期

荣誉与奖励

1.  第八届“国药工程—东富龙杯”全国大学生制药工程设计竞赛二等奖（指导教师）

2.  第十三届“挑战杯”河南省大学生课外学术科技作品竞赛二等奖（指导教师），

3.  2020 年度河南省教育厅科技成果奖优秀科技论文奖二等奖，（第一位）

4. 2019年校级教学新秀奖比赛一等奖