irrespective of sth 不受某事物影响；不考虑某事物；不问某事物 ≈ regardless
例句
They have to give so much thought and attention to the low-level mechanics of handling the ball or fingering the keys or reading the music, that they are unable to give any thought to the thing that matters – the game or the music respectively.
The course is open to anyone, irrespective of age. 这门课任何人都可参加，没有年龄限制。