Enzymes (Mr. W’s Enzyme Music Video)

They’re the protein catalysts in every organism — ENZYMES!
Through enzymatic action your metabolism’s driven — ENZYMES!
In staphylococcus, jellyfish, tarantulas and trees,
They lower activation energy — Enzymes, in you and me now — ENZYMES!

You got ’em in your cells where they do cellular digestion, — ENZYMES!
You got ’em in your mouth and in your stomach and intestines — ENZYMES!
The thing an enzyme acts upon is called a substrate.
They fit like lock and key with complementary shape —
Enzymes, speed up reaction rates — ENZYMES!

An enzyme binds its substrate at its active site — ENZYMES!
Bound together in a complex where they snuggle so tight, — ENZYMES!
New bonds will form and break due to the active site’s chemistry,
Reactants become products, it’s the enzyme’s specialty,
Product gets release — enzyme repeats its action readily — ENZYMES!

Like any molecule an enzyme’s shape defines its function. — ENZYMES!
Environmental change that changes shape leads to malfunction, — ENZYMES!
Every enzyme has a pH where it catalyzes best,
a pH change will set enzyme activity to rest.
Enzymes are so sensitive they’re easily upset — ENZYMES!

More heat until a certain point increases their efficiency — ENZYMES!
But too much heat denatures them destroying their activity — ENZYMES!
That’s why a fever running high’s a dangerous situation,
All that heat can alter enzymatic conformation.
Keep it 98.6 for enzyme optimization — ENZYMES!

Enzymes in saliva will break starch into glucose — ENZYMES!
If you lack the enzyme lactase then you won’t enjoy milk lactose, — ENZYMES!
Tay-sachs, galactosemia and PKU disease,
All caused by inherited enzyme deficiencies —
ENZYMES, they’re what everybody needs — ENZYMES!