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1 5.4.1 About&...
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2 5.4.2 Talkin...
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3 5.4.3 The&nb...

在这个单元里,我们将谈论人过去的性格、外貌特点及喜好等,借此学习used to这一特有的,用来表述过去经历和习惯的语言结构。在本课的学习中,我们将一起走入哈利波特这部电影的戏里戏外,看一看经过14年,哈利波特和他的朋友们都长成什么样了?并且讨论一下哈利波特在成长过程中性格发生了哪些变化。



A Single DNA Difference in the HERC2 Gene Explains Blue Eyes
A new study published in Human Genetics by Eiberget. al. shows that a DNA change in the HERC2 gene causes blue eyes. Two other studies, a study by Kaser et. al. and a study by Sturm et. al. used different approaches to find the same thing. HERC2 is a surprise since it doesn't seem tobe involved in eye color.
But the nearby OCA2 gene is. The researchers think that the DNA difference in HERC2 results in the shutting off of the OCA2 gene.And that a non-working OCA2 gene is one of the steps needed for blue eyes.
This is different than the results published last February that pointed to three DNA differences in the OCA2 gene itself that led to blue eyes. However, these three differences are very near the new difference and only explained about 2/3 of the cases of blue eyes. Most likely these differences are linked to blue eyes but don't cause them.
The researchers also found that all the blue-eyed people they looked at had the exact same DNA difference. This suggests that all of these folks came from the same blue-eyed ancestor. More analysis suggested that this blue-eyed ancestor migrated to Europe 6000-10,000 years ago where the gene spread like wildfire.
Close only Counts in Horseshoes, Hand Grenades, and Blue Eyes
Eye color happens because of the amount of the pigment melanin found in the front part of the iris. Little or no melanin there gives blue eyes. Lots of melanin in the iris gives brown eyes.
Within the last few years, scientists have identified the OCA2 gene as a major player in determining eye color. OCA2 is akey gene that's involved in determining how much melanin is made.
Some versions of OCA2 cause lots of pigment to be made and lead to brown eyes. Other versions that cause little or no pigment to get made lead to eye colors other than brown*. These other versions don't necessarily give blue eyes, though, because there are other eye color genes besides OCA2.
So how would a single mutation in a gene account for eye color? Well, there are lots of ways that this could happen. For instance, since OCA2 controls pigmentation, if it were broken, cells wouldn't have pigment. This is actually what happens in some types of albinism.
But most people with blue eyes do not have albinism. They just lack pigment in the eyes. To understand how a gene could work in one place but not in another, we need to go into a little more detail about genes.



