金属有机化学
杭州师范大学
主讲教师：李世军
有机金属化学是一门新兴的交叉学科，其发展速度非常快。在本课程中，学生将学习金属有机化学的历史，以及金属有机化合物的结构、键合和反应，重点介绍金属有机化学的基本原理和基元反应，从基元反应的角度对金属有机化合物参与的有机合成反应进行归纳和详尽分析，还介绍如何从基元反应出发设计新的有机合成反应。此外，还在理解反应机理的基础上学习金属化、取代、消除、工业上重要的催化循环、及亲电和亲核反应等。课程讲授中充分反映当前有机合成中金属有机化学的发展动态，及对于反应设计能力的培养。要求学生熟练掌握金属有机化学的基本原理和基元反应，并能够灵活应用基元反应来阐析反应机理，初步掌握从基元反应出发设计新的有机合成反应。
Organometallic chemistry is an interdisciplinary science which continues to grow at a rapid pace. Although there is continued interest in synthetic and structural studies the last decade has seen a growing interest in the potential of organometallic chemistry to provide answers to problems in catalysis synthetic organic chemistry and also in the development of new materials. In this course, the students will study the history of organometallic chemistry, as well as the structure, bonding, and the reactions of organometallic compounds, with emphasis on basic mechanisms. The basic principles and elementary reactions of metal-organic chemistry are introduced, and the organic synthesis reactions in which organometallic compounds are involved are summarized and analyzed in detail from the point of view of elemental reactions. This course also introduces how to design a new organic synthesis reaction based on the elementary reaction. Additionally, metalation, substitution, elimination, industrially important catalytic cycles, and electrophilic reactions are considered on a mechanistic basis. Although this course is concerned primarily with transition metal organometallic chemistry, the properties of s and p block organometallics may be considered.
…
| 学校： | 杭州师范大学 |
| 课程编号： | 0090203018 |
以课堂讲授为主，多媒体结合板书。要求学生课内学习与课外自习相结合。通过课外自主学习巩固课内学习内容。根据本课程的特点对具体教学方法和形式提出如下建议：
（1）本课程是一门专业基础课，是以无机化学、有机化学、物理化学等为基础的研究生专业课程，有较多复杂的结构式和反应式，比较难学，合理控制教学内容总量，基础理论以必需、够用为度，贯彻“少而精”的原则，降低教学难度。
（2）本课程通过具体的过渡金属催化实例，讲解金属有机化合物的结构与性质、相互转化、催化机理等，需要熟练掌握基元反应，并能够灵活运用基元反应解析反应机理。
（3）本课程实践性较强，理论要紧密结合实际。
Mainly rely on lectures in the classroom by usingmultimedia combined with the board. Students are required to combine in-classstudy with extracurricular self-study and to consolidate in-class learningcontent through extracurricular self-learning. According to the characteristicsof this course, the following suggestions are given for specific teachingmethods:
(1) Thiscourse is a professional basic course. It is a postgraduate course based oninorganic chemistry, organic chemistry, physical chemistry, etc. It has morecomplicated structural and reactive forms, so it is more difficult to learn andneed control the total amount of teaching content. The basic principle is"necessary and sufficient theory" and “less and finer” to reduce thedifficulty of teaching.
(2) Thiscourse introduces the structure and properties of metal organic compounds,mutual transformation, catalytic mechanism, etc. through specific examples oftransition metal catalysis. It is necessary to master the elementary reactionand skillfully apply the reaction mechanism of elementary reaction.
(3) Thiscourse is practical and the theory should be closely integrated with applications.